I have both rheumatoid and osteo arthritis in both hands. I have tried many different CBD topicals and found them to be essentially a menthol rub. Sort of helps for 5 minutes. So when I was offered this salve as a free sample, I was pretty skeptical. I put it only on one of my two hands (the one that was hurting more at the time). I did not rub it in, because that would get it on the other hand. Rather, I just let it air dry and didn't touch anything for 30 minutes or so. Not only did it help notably, but even 12 hours later, the untreated hand was hurting quite a bit more than the treated hand. I was stunned. Great product!